Primary Identifier | MGI:3858304 | Allele Type | Gene trapped |
Attribute String | Reporter | Gene | Slk |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Sanger Inst. Gene Trap Res. |
molecularNote | The gene trap vector inserted in intron 10. The insertion results in an in-frame splicing event and the expression of a fusion protein that lacks amino acids 795-1202 and is approximately 50 kDa larger than the endogenous protein. The fusion protein retains the catalytic kinase domain as well as the central coiled-coil region but lacks the ATH domain. |