Primary Identifier | MGI:4329457 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Prpf3 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene trap vector pGT2lxf inserted after exon 2. Southern blot analysis indicates that this insertion results in deletion of a significant portion of the gene including exons 3 - 14. Northern and western blot analysis detected about a 30% reduction in expression in retinas from heterozygous mice. |