| Primary Identifier | MGI:4330710 | Allele Type | Gene trapped |
| Attribute String | Hypomorph, Reporter | Gene | Vrk1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Insertion of a beta-gal and neo cassette within 6174 bases 3' of the beginning of intron 3 of Vrk1. The predicted product only contains the N-terminal 72 amino acids fused with beta-gal and is catalytically inert. However, RT-PCR demonstrated only a 4.5- to 6.4-fold decrease in full length message in various adult tissues, confirmed by immunoblots, indicating this is a hypomorphic allele. |
