| Primary Identifier | MGI:4332298 | Allele Type | Gene trapped |
| Attribute String | Null/knockout, Reporter | Gene | Tdp2 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The trapping vector pGT0lxf was inserted into intron 5. Quantitative PCR and FISH analysis indicated that more than 40 copies of the vector had integrated in a single site. No beta-galactosidase staining was detected during embryogenesis; however, lacZ mRNA expression is detected. RT-PCR analysis detected the presence of wild-type mRNA in homozygous trapped mice. Further analysis revealed a partial duplication of the wild-type gene including exons 1 - 5 that appeared to be inserted after the tandem vector insertion. |
