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Allele : Plekhg5<Gt(E277F07)Wrst> pleckstrin homology domain containing, family G (with RhoGef domain) member 5; gene trap E277F07, German Gene Trap Consortium

Primary Identifier  MGI:4352190 Allele Type  Gene trapped
Attribute String  Null/knockout Gene  Plekhg5
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The gene trap cassette inserted into intron 4. RT-PCR analysis showed that the mutation eliminated normal mRNA expression of all four known isoforms of the gene. A fusion protein consisting of the first 28 amino acids fused to beta-GEO is expressed from this allele. No wild-type protein is detectable in immunostaining experiments.
  • mutations:
  • Insertion of gene trap vector
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories