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Allele : Gt(ROSA)26Sor<tm8(RNAi:Crhr1)Rkuhn> gene trap ROSA 26, Philippe Soriano; targeted mutation 8, Ralf Kuhn

Primary Identifier  MGI:4353628 Allele Type  Targeted
Gene  Gt(ROSA)26Sor Transmission  Germline
Strain of Origin  (C57BL/6J x 129S6/SvEvTac)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Using RMCE, an inserted hygro cassette was replaced with a neo cassette and a short hairpin RNA driven by the human U6 promoter that targets Crhr1. Expression of the shRNA results in an 80% reduction in endogenous Crhr1 transcript levels compared to in wild-type mice.
  • mutations:
  • Insertion
  • synonyms:
  • shCRHR1,
  • shCRHR1
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories