| Primary Identifier | MGI:4353633 | Allele Type | Targeted |
| Gene | Gt(ROSA)26Sor | Transmission | Germline |
| Strain of Origin | (C57BL/6J x 129S6/SvEvTac)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Using RMCE, an inserted hygro cassette was replaced with a neo cassette and a short hairpin RNA driven by the human U6 promoter that targets Lrrk2. Expression of the shRNA results in an 82% decrease in endogenous Lrrk2 transcript expression in the brain. |
