|  Help  |  About  |  Contact Us

Allele : Tsc2<tm2.1Djk> TSC complex subunit 2; targeted mutation 2.1, David J Kwiatkowski

Primary Identifier  MGI:4354599 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Tsc2
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP and a loxP-neo-loxP cassette flanked exon 3 of Tsc2 which consists of 111 bp, encoding 37 amino acids near the N terminus of the protein (note that in some schemes this is counted as exon 4; however in accordance with human TSC2 gene, it is denoted this as exon 3, labeling a 5' untranslated exon as 1a). The neo cassette was removed in ES cells by transient cre expression leaving exon 3 floxed.
  • mutations:
  • Insertion
  • synonyms:
  • Tsc2<c-del3>,
  • Tsc2<c-del3>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

9 Publication categories