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Allele : Tsc2<tm2.2Djk> TSC complex subunit 2; targeted mutation 2.2, David J Kwiatkowski

Primary Identifier  MGI:4354601 Allele Type  Targeted
Attribute String  Hypomorph Gene  Tsc2
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 3 of Tsc2 which consists of 111 bp, encoding 37 amino acids near the N terminus of the protein (note that in some schemes this is counted as exon 4; however in accordance with human TSC2 gene, always denoted this as exon 3, labeling a 5' untranslated exon as 1a) was removed from the Tsc2tm2Djk locus by crossing with mice expressing Cre recombinase in the germline. This allele is hypomorphic allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Tsc2<del3>,
  • Tsc2<del3>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories