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Allele : Adam17<tm1.2Bbl> a disintegrin and metallopeptidase domain 17; targeted mutation 1.2, Carl P Blobel

Primary Identifier  MGI:4354847 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Adam17
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a loxP site and frt-flanked PGK-neo cassette upstream of exon 2, and a second loxP site downstream of exon 2 of the targeted gene. The resulting mutant mice were then bred to mice expressing Flp recombinase to remove the frt-flanked neo cassette.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

48 Publication categories