|  Help  |  About  |  Contact Us

Allele : Ptprc<m1Btlr> protein tyrosine phosphatase receptor type C; mutation 1, Bruce Beutler

Primary Identifier  MGI:4355241 Allele Type  Chemically induced (ENU)
Gene  Ptprc Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced A to T transversion at position 74078 of the genomic DNA sequence (Genbank genomic region NC_000067 for linear genomic DNA sequence of Ptprc). The mutated residue corresponds to nucleotide 1407 and nucleotide 990, respectively, in the cDNA sequences of Ptprc isoform 1 (NM_001111316) and isoform 2 (NM_011210). The mutation converts lysine 422 (isoform 1) or 283 (isoform 2) of the CD45 protein to a stop.
  • mutations:
  • Single point mutation
  • synonyms:
  • belittle,
  • belittle
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories