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Allele : Ikzf2<tm1Kast> IKAROS family zinc finger 2; targeted mutation 1, Philippe Kastner

Primary Identifier  MGI:4355173 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ikzf2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin cassette replaced the segment of exon 7 that lies between SalI and XbaI restriction sites. This mutation deleted sequences that encode the C-terminal zinc finger domains. The locus produced truncated mRNA as determined by RT-PCR. No protein was detected in immunoblot analysis of homozygote thymus extracts using an antibody specific to the N-terminal of the protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Helios<->,
  • Helios<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

12 Publication categories