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Allele : Etv6<tm1(RUNX1)Haho> ets variant 6; targeted mutation 1, Hanno Hock
Primary Identifier  MGI:4355899 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, No functional change Gene  Etv6
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 6 and 7 were replaced with a floxed neo, floxed STOP, and human RUNX1 coding region. When the floxed neo and STOP cassette are removed by cre-mediated recombination, a fusion product of mouse Etv6 and human RUNX1 (or TEL-AML1) was created.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • TEL-AML1,
  • TEL-AML1
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

5 Publication categories





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