| Primary Identifier | MGI:4356428 | Allele Type | Targeted |
| Attribute String | No functional change, Not Applicable | Gene | Snord116 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| description | Cre mediated recombination of this allele in combination with Ipwtm1Jbro yields Del(7Ipw-Snord116)1Jbro. |
| molecularNote | A cassette containing the 5' half of the HPRT mini-gene (driven by the Pgk promoter), a loxP site and a neomycin resistance gene (driven by the Polr2a promoter), was inserted 5' of Snord116. Mice with this allele don't display a discernible phenotype. When expressed from the maternal allele, this construct forces the expression of the snoRNA genes in the, normally maternally imprinted, Snord116 and Snord115 clusters. |
