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Allele : Arx<tm2Kki> aristaless related homeobox; targeted mutation 2, Kunio Kitamura

Primary Identifier  MGI:4359175 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Arx
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with one in which nucleotide substitutions result in the amino acid substitution of proline with arginine at position 355 in the encoded protein (p.P355R), mimicking a mutation found in some X-linked lissencephaly patients. A neomycin resistance gene cassette was inserted into intron 2.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Arx<P355R>,
  • Arx<P355R>,
  • Arx<PR>,
  • Arx<PR>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

5 Publication categories