| Primary Identifier | MGI:4359177 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Arx |
| Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2 was replaced with one in which coding nucleotide 330 (C), the third base of alanine codon 110 in the middle of the first poly-alanine stretch, was replaced with a G and had seven GCG alanine codons inserted after it (c.330C>GGCGGCGGCGGCGGCGGCGGCG). The resulting protein mutation (p.(A110_A111delinsAAAAAAAAA)) mimics a muation found in some X-linked mental retardation patients. A neomycin resistance gene cassette was inserted in to intron 1. |
