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Allele : Map3k14<m1Btlr> mitogen-activated protein kinase kinase kinase 14; mutation 1, Bruce Beutler

Primary Identifier  MGI:4357692 Allele Type  Chemically induced (ENU)
Gene  Map3k14 Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  This mutation, identified in a screen of G3 progeny of an ENU mutagenized mouse for failure to mount a humoral immune response to a model antigen, comprises a C to T transition at nucleotide position 1269 of the genomic sequence, in the sixth of the gene's 16 exons. It replaces the codon specifying arginine at position 396 with a termination codon (R396Ter).
  • mutations:
  • Single point mutation
  • synonyms:
  • lucky,
  • lucky
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories