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Allele : Pfkm<tm1Fbos> phosphofructokinase, muscle; targeted mutation 1, Fatima Bosch

Primary Identifier	MGI:4356541	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Pfkm
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 3 was replaced with a neo cassette. The absence of transcript expression was confirmed by northn blot analysis on muscle extracts.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Garcia M, et al. (2009) Phosphofructo-1-kinase deficiency leads to a severe cardiac and hematological disorder in addition to skeletal muscle glycogenosis. PLoS Genet 5(8):e1000615

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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