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Allele : Tg(Mef2c-lacZ)5Blk transgene insertion 5, Brian L Black

Primary Identifier	MGI:4356545	Allele Type	Transgenic
Attribute String	Reporter	Gene	Tg(Mef2c-lacZ)5Blk
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

A 44 bp segment of the F10 fragment located in intron 5 of Mef2c and containing the FOX:ETS motif was used to direct expression of lacZ by the Hspa1b minimal promoter. Lac Z expression is specific to endothelial cells during early embryogenesis. Enhancer activity is extinguished after E10.5.

mutations:
Insertion

synonyms:
Mef2c - F10-44-lacZ,
Mef2c - F10-44-lacZ

earliestPublication:
De Val S, et al. (2008) Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors. Cell 135(6):1053-64

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

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