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Allele : Lat<tm5.1Mal> linker for activation of T cells; targeted mutation 5.1, Bernard Malissen
Primary Identifier  MGI:4357969 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lat
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Deletion of exons 1 to 12 occurred by replacement with an autodeleting cre+neo cassette (loxP site, the mouse Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1) promoter, the cre recombinase gene, a neomycin resistance gene cassette, and a second loxP site). The whole coding region was removed.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Lat tm5mal,
  • B6-Lat null,
  • Lat tm5mal,
  • Lat<tm5Mal>,
  • Lat<tm5Mal>,
  • B6-Lat null
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





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