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Allele : Gpbar1<tm1.1Auw> G protein-coupled bile acid receptor 1; targeted mutation 1.1, Johan Auwerx

Primary Identifier	MGI:4359278	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Gpbar1
Transmission	Germline	Strain of Origin	129/Sv
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 1 and a floxed and frt-flanked neo cassette was inserted downstream of exon 1. Flp mediated recombination removed the neo cassette leaving exon 1 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
TGR5<L2>,
TGR5<L2>

earliestPublication:
Thomas C, et al. (2009) TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab 10(3):167-77

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

10 Publication categories

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