Primary Identifier | MGI:4360711 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase, Reporter | Gene | Tg(Pcp2-cre/ERT2,-ALPP)1Alj |
Strain of Origin | FVB/N | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A 3kb genomic fragment containing a truncated Pcp2 enhancer and gene drives cre/ERT2 followed by an IRES-ALPP (human placental alkaline phosphatase) sequence. The construct was injected into FVB/N oocytes and four founders were obtained. The line displaying the strongest expression in embryonic Purkinje cell (PC) clusters and adult medial-lateral PC stripes was chosen for further analysis. |