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Allele : Tg(Col2a1-rtTA,tetO-COMP*)2Jath transgene insertion 2, Jacqueline Hecht

Primary Identifier  MGI:4361028 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence, Transactivator Gene  Tg(Col2a1-rtTA,tetO-COMP*)2Jath
Strain of Origin  C57BL/6 Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  Bigenic mice contain a rtTA driven by the mouse Col2a1 promoter and human COMP, with the deletion del469D found in patients with pseudoachondroplasia, driven by the tetO promoter. Three lines were generated (no line names given).
  • mutations:
  • Insertion
  • synonyms:
  • Tg(Col2a1-rtTA,TRE-COMP*)2Jath,
  • MT-COMP,
  • MT-COMP,
  • Tg(Col2a1-rtTA,TRE-COMP*)2Jath
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

8 Publication categories