Primary Identifier | MGI:4361521 | Allele Type | Targeted |
Gene | Ifngr1 | Transmission | Germline |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 7 contains a nucleotide substitution (TAT -> TTT) that results in the amino acid substitution of tyrosine with phenylalanine at position 441 (Y441F). A downstream floxed neo was removed by germ line, cre mediated recombination. The mutated amino acid is within the Socs1 binding site. |