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Allele : Tg(Myh6-CREB1*S133A)1Jml transgene insertion 1, Jeffrey M Leiden

Primary Identifier  MGI:4360273 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh6-CREB1*S133A)1Jml
Strain of Origin  CD-1 Is Recombinase  false
Is Wild Type  false
molecularNote  The human open reading frame with nucleotide substitutions that result in the amino acid substitution of alanine for serine at position 133 was inserted into a vector containing the promoter and untranslated exons 1 through 3 of the murine promoter followed by an SV40 polyadenylation sequence. Transgene promoter drives expression in cardiac myocytes. Three founder lines were established (lines 1, 2, and 3) with between 15 and 50 cpoies of the transgene, respectively.
  • mutations:
  • Insertion
  • synonyms:
  • CREB<A133>,
  • CREB<A133>,
  • CREB<A133>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories