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Allele : Atn1<tm1Rexu> atrophin 1; targeted mutation 1, Rener Xu

Primary Identifier  MGI:4360645 Allele Type  Targeted
Attribute String  Null/knockout Gene  Atn1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-Neo cassette was inserted into exon 5 by homologous recombination to introduce a premature "TAG" stop codon and produce a truncated protein of 416 amino acids with an intact N-terminus but lacking both the poly-Q stretch and following C-terminal peptides. Protein was detected at a level similar to that of the wild-type protein (1,175 amino acids) in brain samples.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Atn1<t>,
  • Atn1<t>,
  • Atn1<t>,
  • Atn1<t>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories