|  Help  |  About  |  Contact Us

Allele : Cdk4<tm1(KOMP)Wtsi> cyclin dependent kinase 4; targeted mutation 1, Wellcome Trust Sanger Institute

Primary Identifier  MGI:4363499 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Cdk4
Transmission  Cell Line Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The insertion of the L1L2_Bact_P cassette created a deletion of size 1725 starting at position 126900406 and ending at position 126902131 of Chromosome 10 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site.
  • mutations:
  • Intragenic deletion,
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories