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Allele : Tg(Vim*R113C)1Tmm transgene insertion 1, Thomas M Magin

Primary Identifier  MGI:4365636 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Vim*R113C)1Tmm
Strain of Origin  CBA Is Recombinase  false
Is Wild Type  false
molecularNote  An 18 kb segment containing 10.5 kb of 5'- and 1 kb of 3'-regulatory sequence was isolated from a BALB/c cosmid library. The myc epitope was introduced by site-directed mutagenesis after serine at the second amino acid position.An additional mutation was introduced by site-directed mutagenesis that resulted in an arginine to cytosine change at amino acid residue 113. The transgenic mouse line was generated from a founder animal expressing the mutant at sub-stoichiometric level (<=30%) compared with the endogenous gene.
  • mutations:
  • Insertion
  • synonyms:
  • Vim R113C,
  • Vim R113C
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories