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Allele : Pvalb<tm1(cre/ERT2)Zjh> parvalbumin; targeted mutation 1, Z Josh Huang

Primary Identifier  MGI:4365738 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Pvalb
Transmission  Germline Strain of Origin  C57BL/6
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false Project Collection  Neuroscience Blueprint cre
molecularNote  A targeting vector was designed to insert a CreERT2 fusion gene (Cre-ERT2; Cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain), an SV40 polyA signal, and an frt-flanked neo cassette into the initiation codon of the Pvalb (parvalbumin; also called PV or Pva) gene. Mutant mice were bred with Actin-FLPe mice (on a C57BL/6 congenic background) to remove the neo selection cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Pv-CreER,
  • Pv-CreERT2,
  • PV-2A-CreER<T2>,
  • Pv-CreERT2,
  • PV-2A-CreER<T2>,
  • Pv<CreERT2>,
  • Pv<CreERT2>,
  • Pv-CreER
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

16 Publication categories