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Allele : Fasl<tm2.1Ast> Fas ligand; targeted mutation 2.1, Andreas Strasser

Primary Identifier  MGI:4366051 Allele Type  Targeted
Gene  Fasl Transmission  Germline
Strain of Origin  B6.Cg-Thy1<a> Is Recombinase  false
Is Wild Type  false
molecularNote  The protion of the gene encoding the metalloprotease-cleavage site was mutated (SSFEKQI to SEEAAAI) preventing the production of the soluble peptide. However, the membrane version is still produced. The floxed neo cassette used for selection purposes was removed by germ line, cre mediated recombination.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • FasL<deltas>,
  • FasL<deltas>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories