| Primary Identifier | MGI:4365386 | Allele Type | Targeted |
| Gene | Ctsa | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 6 was replaced with one that contains nucleotide substitutions (c.571AGC>GCA) resulting in an amino acid substitution of alanine for serine at position 190 (S190A). A floxed neo cassette was inserted downstream of exon 7 and was removed by germ line cre mdiated recombination. While the protein is expressed almost no enzymatic activity is detected. |
