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Allele : Ctsa<tm1Avps> cathepsin A; targeted mutation 1, Alexey Pshezhetsky

Primary Identifier  MGI:4365387 Allele Type  Targeted
Attribute String  Hypomorph Gene  Ctsa
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 6 contain nucleotide substitutions (c.571AGC>GCA) resulting in an amino acid substitution of alanine for serine at position 190 (S190A). A floxed neo cassette was inserted downstream of exon 7. Transcript expression is reduced indicating that this allele is hypomorphic.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • CathA<S190A-Neo>,
  • CathA<S190A-Neo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories