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Allele : Tg(Aire-G6pc2/GFP)1Mand transgene insertion 1, Mark Anderson

Primary Identifier  MGI:4367724 Allele Type  Transgenic
Attribute String  Reporter Gene  Tg(Aire-G6pc2/GFP)1Mand
Strain of Origin  NOD Is Recombinase  false
Is Wild Type  false
molecularNote  The BAC clone RPCI23, 461E7 was modified by targeted replacement of the coding portion of exon 1, all of exon 2 and part of exon 3 of the Aire gene with a construct containing a beta globin donor and acceptor cassette, a G6pc2/GFP fusion sequence and SV40 polyadenylation signal. The resulting transgene does not express Aire. Two NOD and two C57BL/6 founders were produced. The two NOD founders were propagated.
  • mutations:
  • Insertion
  • synonyms:
  • Adig,
  • Adig
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories