| Primary Identifier | MGI:4368012 | Allele Type | Targeted |
| Attribute String | Inserted expressed sequence | Gene | Ilk |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Lysine codon 220 (AAG) in exon 8 was changed to alanine (p.K220A) and a loxP site flanked neomycin resistance gene cassette was inserted into the 3' UTR in exon 13. The neo cassette was removed through subsequent Cre-mediated recombination. This substitution produces a kinase-dead product with decreased binding to beta-parvin (Parvb). |
