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Allele : Stx3<Gt(EUCE320f12)Hmgu> syntaxin 3; gene trap EUCE320f12, Helmholtz Zentrum Muenchen GmbH

Primary Identifier  MGI:4391716 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Stx3
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A gene trap cassette flanked by inversely oriented pairs of the heterotypic FRT/F3 and lox511/loxP recombinase target sequences was inserted in intron 1 of the gene. Expression of FLP recombinase will invert the gene trap from its sense (mutagenic) orientation to antisense, allowing expression of the gene (floxed allele); subsequent Cre expression will reinduce the mutation by the reinversion of gene trap to its sense orientation, generating a knockout allele.
  • mutations:
  • Insertion of gene trap vector
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories