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Allele : Tg(Myh6-Gata4)1Jmol transgene insertion 1, Jeffery D Molkentin

Primary Identifier  MGI:4399083 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh6-Gata4)1Jmol
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
molecularNote  The GATA binding protein 4 (Gata4) sequence driven by myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6 or alpha-MHC) promoter/enhancer elements. One founder with 15-20 transgenic insertions died within 4 weeks of severe cardiomyopathy. This line was derived from a founder with only 1-3 insertions. Gata4 expression in the heart was increased 2.5 fold.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories