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Allele : Khk<tm2Dtb> ketohexokinase; targeted mutation 2, David T Bonthron

Primary Identifier  MGI:4398729 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Null/knockout Gene  Khk
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A stop codon was introduced into exon 3a preventing the production of the A transcript. A floxed neo cassette was inserted upstream of the modified exon 3a. Exons 4 through 6 and part of 7 were deleted, preventing the production of the C splice variant. Western blot analysis confirmed the absence of isoforms A and C.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • KHK-A/C KO,
  • KHK-A/C KO,
  • Khk<delta>,
  • Khk<delta>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

32 Publication categories