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Allele : Rnf138<tm1.1Lwan> ring finger protein 138; targeted mutation 1.1, Linfang Wang

Primary Identifier	MGI:6834806	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Rnf138
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 2 was flanked by loxP sites and an FRT-flanked neomycin selection cassette was inserted downstream of exon 2 before the second loxP site. Exon 2 and the selection cassette were removed via cre-mediated recombination. Exon 2 deletion results in a downstream frameshift.

mutations:
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Xu L, et al. (2017) Rnf138 deficiency promotes apoptosis of spermatogonia in juvenile male mice. Cell Death Dis 8(5):e2795

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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