Primary Identifier | MGI:4398965 | Allele Type | Transgenic |
Attribute String | Reporter | Gene | Tg(Hmgcr-lacZ)1Dym |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The construct consists of 4.5 kb of the mouse Hmgcr promoter/enhancer sequences driving a lacZ reporter sequence with a nuclear localization signal. The reporter is disrupted by an FRT-flanked neo cassette. Flp recombinase-mediated recombination results in restoration of the lacZ transcript. |