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Allele : Zap70<tm2.1Weis> zeta-chain (TCR) associated protein kinase; targeted mutation 2.1, Arthur Weiss

Primary Identifier  MGI:4399123 Allele Type  Targeted
Gene  Zap70 Transmission  Germline
Strain of Origin  129S4/SvJae Is Recombinase  false
Is Wild Type  false
description  ES cells used contained Tg(Prm-cre)70Og
molecularNote  Residues Y315 and Y319 present in exon 7 of ZAP-70 were mutated to alanine. A diagnostic EcoRV site was also introduced into exon 7 as well as a floxed neo cassette in intron 2. Cre mediated recombination in the male germline subsequently removed the neo cassette.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • YYAA,
  • YYAA
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

5 Publication categories