| Primary Identifier | MGI:4399218 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Irx1 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | KOMP-Regeneron |
| molecularNote | The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 4980bp between positions 72106625-72111604 of Chromosome 13 (Build GRCm39). All 4 exons (i.e. the entire sequence from start codon to stop codon) were replaced with a lacZ reporter and a floxed neomycin resistance cassette. qRT-PCR and Western blot analysis confirmed complete loss of mRNA and protein expression in lung tissue from P0 homozygotes. |
