Primary Identifier | MGI:4411993 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Grm6-icre)1Rlbn |
Strain of Origin | Not Specified | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The transgenic construct contains a 637-bp Grm6 (mGluR6) promoter fragment upstream of a codon-improved cre (iCre) and a polyadenylation sequence. A 9.5 kb fragment of the Grm6 5' upstream region was inserted to reconstitute the full-length Grm6 promoter. The construct was injected into fertilized oocytes and two founder lines were obtained. Only one line was found to express cre in the retina. |