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Allele : Rr92<tm1.1Brts> regulatory region 92; targeted mutation 1.1, Brett T Spear
Primary Identifier  MGI:4413473 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout Gene  Rr92
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Three enhancers between the Alb and Afp genes were replaced with a loxP site flanked neomycin resistance gene cassette. Cre-mediated recombination removed the neo cassette. Early transcript expression of Alb and Afp is reduced, as confirmed by whole mount in situ hybridization on E10.5 embryos.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • enh<->,
  • enh<->,
  • Afp/Alb<tm1.1Brts>,
  • Afp/Alb<tm1.1Brts>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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