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Allele : Clcn7<tm3.1Tjj> chloride channel, voltage-sensitive 7; targeted mutation 3.1, Thomas J Jentsch

Primary Identifier	MGI:4413670	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Clcn7
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was upstream of exon 12 and a floxed neo cassette was inserted downstream of exon 13. Cre mediated recombination removed the neo cassette leaving exons 12 and 13 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Clcn7<lox>,
Clcn7<lox>

earliestPublication:
Wartosch L, et al. (2009) Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7. FASEB J 23(12):4056-68

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

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