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Allele : Cyp3a<tm1.1Arte> cytochrome P450, family 3, subfamily a cluster; targeted mutation 1.1, TaconicArtemis
Primary Identifier  MGI:4414654 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cyp3a
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1 and 2 of Cyp3a57 were replaced with a hygromycin cassette containing a loxP site and subsequently inserting a neomycin cassette with a loxP site into intron 4 of Cyp3a59. Cre-mediated recombinase resulted in the deletion of Cyp3a57, Cyp3a16, Cyp3a41, Cyp3a44, Cyp3a11, Cyp3a25, and exons 1 to 4 and the promoter of Cyp3a59.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • Del(5Cyp3a57-Cyp3a59)1Arte,
  • Cyp3a<->/3a13<+>,
  • Del(5Cyp3a57-Cyp3a59)1Arte,
  • Cyp3a<->/3a13<+>
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1 Feature

Genome

0 Expresses

26 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

11 Publication categories





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