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Allele : Lrrk2<tm1.1Cai> leucine-rich repeat kinase 2; targeted mutation 1.1, Huaibin Cai

Primary Identifier  MGI:4414662 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lrrk2
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into intron 1 and an frt-flanked neo cassette with a second loxP site was inserted into intron 2. Cre mediated recombination removed the neo cassette and exon 2. The absence of protein expression was confirmed by western blot analysis on brain extracts.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

26 Publication categories