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Allele : Tg(tetO-LRRK2*G2019S)1Cai transgene insertion 1, Huaibin Cai
Primary Identifier  MGI:4414665 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence Gene  Tg(tetO-LRRK2*G2019S)1Cai
Strain of Origin  Not Specified Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The tet operator drives expression of the human cDNA with nucleotide substitutions that result in the amino acid substitution of serine for glycine at position 2019 (G2019S). This mutation is commonly observed in patients with Parkinson's disease and is thought to increase the kinase activity of the protein. No line information given.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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