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Allele : Tg(CAG-EGFP,RNU6-RNAi:Sly)367Psb transgene insertion 367, Paul S Burgoyne

Primary Identifier  MGI:4415346 Allele Type  Transgenic
Attribute String  Knockdown, Reporter Gene  Tg(CAG-EGFP,RNU6-RNAi:Sly)367Psb
Strain of Origin  (CBA/Ca x C57BL/10)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A CAG promoter drive ubiquitous expression of EGFP and the human U6 shRNA promoter (RNU6) drives ubiquitous expression of a short hairpin RNA targeting Sly. Two lines were created (line 136 and 367). Western blot analysis confirmed the absence of endogenous Sly protein expression in both lines. Line 367 was selected as the representative line.
  • mutations:
  • Insertion
  • synonyms:
  • sh367,
  • sh367
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories