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Allele : Icos<tm1Wks> inducible T cell co-stimulator; targeted mutation 1, Woong-Kyung Suh
Primary Identifier  MGI:4415347 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Icos
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Tyrosine 181 in exon 3 was mutated to phenylalanine by a single A-T transversion. A diagnostic EcoRI site was also introduced into exon 3 as well as a floxed neo cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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