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Allele : Nr1h3<tm1Wexi> nuclear receptor subfamily 1, group H, member 3; targeted mutation 1, Wen Xie
Primary Identifier  MGI:4415263 Allele Type  Targeted
Attribute String  Constitutively active Gene  Nr1h3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence spanning part of exon 2 through 7 was replaced with a cDNA fused to VP16 activation domain and followed by an SV40 polyadenylation site and neo cassette. This fusion is predicted to create a constitutively active form.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • VP-LXRalpha,
  • VP-LXRalpha,
  • LXR-KI,
  • LXR-KI
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





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